The Genetics And Psychosis (GAP) study
As part of this wide study focussing on genetic factors associated with onset of psychosis, we investigated cortisol and inflammatory markers in relation to brain structure and clinical outcome in individuals experiencing the first episode of psychosis. As part of this study, we have been the first to describe an abnormal biological response to stress at the onset of psychosis. As part of our work in this study, we identified the biological response to stress as one of the factors contributing to the brain abnormalities found at psychosis onset and we showed that biomarkers of stress predict poor clinical outcome in first episode psychosis.
Recruitment: Closed
Research/Analysis: Complete
Publications:
