The BIOmarkers in DEPression (BIODEP) study

This study is a multi-centre observational study that sees the collaboration between Brighton, Cambridge, Glasgow, London (King’s College), and Oxford. The study aimed to investigate immune-related biomarkers and profiles in patients with depression, stratified also for treatment exposure (responders, non-responders, and drug free). We found that the severity of childhood trauma experience contributed to a lack of response to antidepressant treatment.

Recruitment: Closed

Research/Analysis: Ongoing

Publications

• Sforzini et al., 2023;

• McLaughlin et al., 2021;

• Turkheimer et al., 2021;

• Shubert et al., 2021;

• Cattaneo et al., 2020;

• Lynall et al., 2020;

• Nikkheslat et al., 2020;

• Chamberlain et al., 2019;

• Lynall et al., 2019;

• Chamberlain et al., 2018.