The MINocycline in DEPression (MINDEP) study
This is a placebo-controlled randomised clinical drug trial that investigated the efficacy of add-on minocyline treatment (an antibiotic with anti-inflammatory and antidepressant proprieties) in patients with treatment-resistant depression who were selected for evidence of increased inflammation. We found that add-on treatment with minocycline was effective only in patients with low-grade inflammation.
Recruitment: Closed
Research/Analysis: Ongoing
Publications