The MINocycline in DEPression (MINDEP) study

This is a placebo-controlled randomised clinical drug trial that investigated the efficacy of add-on minocyline treatment (an antibiotic with anti-inflammatory and antidepressant proprieties) in patients with treatment-resistant depression who were selected for evidence of increased inflammation. We found that add-on treatment with minocycline was effective only in patients with low-grade inflammation.

Recruitment: Closed

Research/Analysis: Ongoing

Publications

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The BARIatric Surgery and DEPression (BARIDEP) study

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The BIOmarkers in DEPression (BIODEP) study